Worst ssri for sex disfunction. One randomized placebo controlled trial involving 98 women experiencing antidepressant induced sexual dysfunction concluded that sildenafil significantly reduced the adverse sexual effects, such as delayed orgasm responses and inadequate lubrication.

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However, the longer the drug holiday the higher the risk of depressive symptoms recurring.

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Clayton et al 51 concluded from their double-blind comparison study involving 42 clients with SSRI-induced sexual dysfunction that bupropion SR was an effective antidote.

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Discontinuation of use and switching of antidepressants:

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If you take Zoloft sertraline or Paxil you may be able to schedule a two-day drug holiday each week in order to restore sexual function without losing the benefits of the antidepressant.

All the time without Mirtazapin, I did not.

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However, a number of writers suggest that, in all probability, the difference in rates is due to substantial underreporting rather than under occurrence.

Hall-Flavin, M.