However, the longer the drug holiday the higher the risk of depressive symptoms recurring.
Clayton et al 51 concluded from their double-blind comparison study involving 42 clients with SSRI-induced sexual dysfunction that bupropion SR was an effective antidote.
Discontinuation of use and switching of antidepressants:
If you take Zoloft sertraline or Paxil you may be able to schedule a two-day drug holiday each week in order to restore sexual function without losing the benefits of the antidepressant.
All the time without Mirtazapin, I did not.
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However, a number of writers suggest that, in all probability, the difference in rates is due to substantial underreporting rather than under occurrence.